An Unanticipated Result in the Pd (0) Catalyzed Coupling of Sodium Adenate withcis-4-Acetyloxy- andcis-4-t-Butyldimethylsilyloxy-2-Cyclopentenyl Diethylphosphate
- 1 March 1996
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 26 (6) , 1209-1221
- https://doi.org/10.1080/00397919608003730
Abstract
The preparation of adenine regioisomers of (+/-)-cis-4-(TBSO)-and (+/-)-cis-4-(AcO)-2-cyclopentene is described using either Pd(0) coupling (silyl ether 2) or chloride displacement (acetyl chloride 10). An unexpected difference in reactivity between TBS- and Ac-O-protected allyl phosphates 2 and 7 in Pd(0) catalyzed coupling with sodium adenate was observed.Keywords
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