Deletion of the terminus region (340 kilobase pairs of DNA) from the chromosome of Escherichia coli.
- 1 June 1985
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 82 (11) , 3766-3770
- https://doi.org/10.1073/pnas.82.11.3766
Abstract
A strain of E. coli with a 7-minute (340 kilobase pairs of DNA) deletion of the terminus region of the chromosome was isolated. This deletion was probably an IS10-promoted event and its extent was characterized by both genetic and DNA hybridization analyses. The most dramatic property of strains harboring this deletion was the absence of the sites that inhibit clockwise- and counterclockwise-traveling replication forks. These strains also grew slowly, produced many nonviable cells, were filamentous, and appeared to have an induced SOS system.This publication has 30 references indexed in Scilit:
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