Cytotoxic activity of 2′,2′-difluorodeoxycytidine, 5-aza-2′-deoxycytidine and cytosine arabinoside in cells transduced with deoxycytidine kinase gene
- 1 May 2002
- journal article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 293 (5) , 1478-1484
- https://doi.org/10.1016/s0006-291x(02)00413-8
Abstract
No abstract availableKeywords
This publication has 23 references indexed in Scilit:
- Gemcitabine combined with continuous infusion 5-fluorouracil in advanced and symptomatic pancreatic cancer: a clinical benefit-oriented phase II studyBritish Journal of Cancer, 2000
- Phase I and Pharmacologic Study of Sequences of Gemcitabine and the Multitargeted Antifolate Agent in Patients With Advanced Solid TumorsJournal of Clinical Oncology, 2000
- Combination Chemotherapy With Carboplatin, Docetaxel, and Gemcitabine in Advanced Non–Small-Cell Lung Cancer: A Phase II StudyJournal of Clinical Oncology, 1999
- Inhibition of protein kinase C activator-mediated induction of p21CIP1 and p27KIP1 by deoxycytidine analogs in human leukemia cells: Relationship to apoptosis and differentiationBiochemical Pharmacology, 1999
- Human thymidine kinase 2: molecular cloning and characterisation of the enzyme activity with antiviral and cytostatic nucleoside substratesFEBS Letters, 1999
- Drug resistance to 5-aza-2 ′ -deoxycytidine, 2 ′ ,2 ′ -difluorodeoxycytidine, and cytosine arabinoside conferred by retroviral-mediated transfer of human cytidine deaminase cDNA into murine cellsCancer Chemotherapy and Pharmacology, 1998
- Cloning of the cDNA and Chromosome Localization of the Gene for Human Thymidine Kinase 2Journal of Biological Chemistry, 1997
- Comparison of the induction of apoptosis in human leukemic cell lines by 2′,2′-difluorodeoxycytidine (gemcitabine) and cytosine arabinosideLeukemia Research, 1995
- 2′,2′-Difluoro-deoxycytidine (gemcitabine) incorporation into RNA and DNA of tumour cell linesBiochemical Pharmacology, 1993
- Kinetic studies on 2',2'-difluorodeoxycytidine (gemcitabine) with purified human deoxycytidine kinase and cytidine deaminaseBiochemical Pharmacology, 1993