Biosynthesis of phlebiarubrone in Phlebia strigosozonata

Abstract
13 C-Labelled precursors and spectral methods show that the terphenyl ring system of phlebiarubrone can be derived from phenylalanine and the methylene group from formate: the relative proportion of doubly-labelled and singly-labelled metabolite reveals the amount of endogenous phenylalanine available for the biosynthesis of phlebiarubrone through the dimerization of a C6–C3 unit.

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