The Systemic Use of Procaine in the Treatment of the Elderly: A Review†

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Abstract
World literature on the systemic use of procaine in the treatment of the aging process and the common chronic diseases of later life are reviewed and evaluated. Included are data from 285 articles and books, describing treatment in more than 100,000 patients in the past 25 yr. Except for a possible antidepressant effect, there was no convincing evidence that procaine (or Gerovital, of which procaine is the major component) has any value in the treatment of disease in older patients. If procaine had an antidepressant effect, there is some likelihood that this accounts for the reports of decreased complaints referable to the musculoskeletal, cardiovascular, endocrine, sexual, gastrointestinal and respiratory systems.