Molecular Identification of 7 Human Papillomavirus Types in Recurrent Respiratory Papillomatosis

Open Access
Publisher Website
Google Scholar
Abstract
RECURRENT respiratory papillomatosis (RRP) is the most frequent benign laryngeal neoplasm, affecting children from the earliest months until adolescence.1 Its approximate incidence is 4.3 per 100,0001; 3870 cases are expected in the Mexican infant population, without sex distinction. It is a benign tumor that rarely becomes malignant after radiotherapy. It begins with a mild dysphonia, which may progress to aphonia, but without signs of respiratory insufficiency. Nevertheless, the clinical findings may be complicated by cough with scarce expectoration, which can result in pneumonia with retention of secretion, acute respiratory insufficiency, and asphyxia.2