THE RADIOAUTOGRAPHIC LOCALIZATION OF 125I-LABELLED BOVINE PARATHYROID HORMONE

1 April 1970

journal article
Published by Bioscientifica in Journal of Endocrinology

Vol. 46 (4) , 507-10
https://doi.org/10.1677/joe.0.0460507

Abstract

The distribution and localization of ¹²⁵I-labelled bovine parathyroid hormone was studied by radioautography in adult rats. The principal site of localization was the proximal convoluted tubule of the kidney. Light and variable localization was present in the liver, but no significant amount of label was found in muscle, spleen, bone or articular cartilage. The localization of this labelled compound in the proximal convoluted tubule suggests that this region degrades ¹²⁵I-labelled parathyroid hormone.

Keywords

RATS
LOCALIZATION
BOVINE
ADULT
HORMONE
PARATHYROID
ARTICULAR
RADIOAUTOGRAPHIC
125I LABELLED

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