Synthesis of Isothiocyanates by Reaction of Amides with Carbon Disulfide in the Presence of Solid Potassium Carbonate/Sodium Hydroxide Mixture
- 1 January 1991
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1991 (11) , 1001-1002
- https://doi.org/10.1055/s-1991-26629
Abstract
Readily available N-monosubstituted trifluoroacetamides are transformed into isothiocyanates in good yield by reaction, at room temperature, with carbon disulfide in acetonitrile in the presence of anhydrous sodium hydroxide/potassium carbonate basic mixture.Keywords
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