Determination of Xylitol in Human Urine by Gas-Liquid Chromatography

Abstract
A rapid and specific method for the quantitative determination of xylitol in human urine has been developed. The method consists of the gas-liquid chromatographic analysis of the acetate ester derivative of the alditol in deionized urine using dulcitol as an internal standard. As little as 20 ng xylitol can be detected. At concentrations ranging from 25 to 400μ g/ml urine, the accuracy is ± 4.0%.

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