Metastatic Orchioblastoma: Alpha1-fetoprotein in Diagnosis and Combination Chemotherapy in Treatment: a Case Report

Abstract
A case in which orchioblastoma metastasised to a lymph node at the left renal hilum is described. The metastasis was not detected by bipedal lymphography, but was associated with a rise in the serum level of the alpha1-fetoprotein. The metastasis responded to combination chemotherapy, including adriamycin, and residual tumour was excised at laparotomy. Tumour regression was associated with a fall in serum alpha1-fetoprotein which may be of value as a tumour marker substance in the diagnosis and monitoring of therapy in this tumour.