Characterization of a new TSPY gene family member in Yq (TSPYq1)
- 27 March 2000
- journal article
- Published by S. Karger AG in Cytogenetic and Genome Research
- Vol. 88 (1-2) , 159-162
- https://doi.org/10.1159/000015510
Abstract
We investigated subinterval 6E on the human Y chromosome, a region frequently deleted in infertile males. YAC yOX17, mapped within subinterval 6E by STS-PCR, was analyzed for the presence of new genes. TSPYq1, a member of the TSPY multi-copy gene family, was isolated and character- ized from a yOX17 cosmid subclone. PCR and FISH analysis performed on normal subjects and on patients with microdeletions of Yq suggested the presence of multiple copies of TSPY in Yq.Keywords
This publication has 1 reference indexed in Scilit:
- Functional Coherence of the Human Y ChromosomeScience, 1997