Muscular Dystrophy. Blood Content of Dystrophic Muscles

Abstract
Blood content of muscle samples obtained on biopsy from muscular dystrophy patients and from control subjects was estimated using 2 radioactive methods. Both methods permit the assay of K42 on the same muscle sample by virtue of the difference in the half lives of the isotopes employed. The blood content of the tissue removed from muscular dystrophy patients is not different from the blood content of normal muscle. This result is obtained by using Cr51 labeled red blood cells. I131 labeled human serum albumin tends to overestimate the blood content of dystrophic tissue, not that of normal muscle. Error may be large if the labeled albumin is injected a long time prior to the biopsy.

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