Zinc Z-DNA
- 1 January 1984
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 12 (8) , 3643-3648
- https://doi.org/10.1093/nar/12.8.3643
Abstract
Circular dichroism spectra of poly(dG-dC) in the presence of some zinc complexes exhibit the characteristic inversion associated with the formation of a left handed helix. The transition of B to Z DNA is cooperative and slow. The concentration of zinc complex at the mid point of the transition is strongly dependent upon the nature of the ligand bound to zinc. The most efficient species is one with a tetradentate amine for which the mid point is observed at a zinc:nucleotide ratio of 1:24. 31P spectra of one of these complexes confirm the presence of a left handed helix.Keywords
This publication has 11 references indexed in Scilit:
- Left-handed helical conformation of poly[d(A-m5C) · d(G-T)]Nature, 1983
- Conditions which cause the right-handed to left-handed DNA conformational transitions. Evidence for several types of left-handed DNA structures in solution.Journal of Biological Chemistry, 1982
- Phosphorus-31 NMR of double- and triple-helical nucleic acidsBiochemistry, 1982
- Left-handed DNA in restriction fragments and a recombinant plasmidNature, 1981
- The transitions between left- and right-handed forms of poly(dG-dC)Nucleic Acids Research, 1981
- High-salt d(CpGpCpG), a left-handed Z′ DNA double helixNature, 1980
- Molecular structure of a left-handed double helical DNA fragment at atomic resolutionNature, 1979
- "Alternating B-DNA" conformation for the oligo(dG-dC) duplex in high-salt solution.Proceedings of the National Academy of Sciences, 1979
- Polymorphism of a synthetic DNA in solutionNature, 1976
- Salt-induced co-operative conformational change of a synthetic DNA: Equilibrium and kinetic studies with poly(dG-dC)Journal of Molecular Biology, 1972