Changes in Moods and Activation Levels During the Menstrual Cycle in Experimentally Naive Subjects

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Abstract
Two experiments providing additional validity data on the Profile of Mood States and the Thayer Activation-Deactivation Adjective Check List were performed. In the third and main experiment, seven normally menstruating women filled out both questionnaires at the same time every day for 90 days. They were not aware that they were participating in a study of menstruation. Analysis of the time series records of individual women revealed relatively few significant fluctuations in moods and activation levels. Analysis of the group data showed that Fatigue, Confusion, Deactivation/Sleep, and Depression/Dejection were significantly lower in the premenstrual phase than in the periovulatory phase of the cycle, while General Activation was higher. Anger/Hostility and Confusion were both lower in the menstrual phase than in the periovulatory phase. On a retrospective menstrual distress questionnaire, these same subjects say that they experience increases in anxiety, irritability, depression, and tension in the premenstrual phase of the cycle. The differences between individual and group data and the apparent discrepancy between daily self-reports and retrospective questionnaires are discussed.