Quantum jumps of conductance during formation of membrane channels at cell–cell junction

Abstract
Cells from Xenopus laevis embryos were studied. Junction between pairs of cells was induced in vitro while continuously monitoring the evolving electrical coupling with a method of high resolution. The cell-to-cell conductance of a nascent cell junction increases by stable quantal steps. The steps evidently reflect the opening of stable cell-to-cell channels, all alike and growing progressively in number.

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