Rapid and Reversible Block of Electrical Activity by Powerful Marine Biotoxins
- 29 July 1960
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 132 (3422) , 300-301
- https://doi.org/10.1126/science.132.3422.300.b
Abstract
Puffer-fish poison and clam poison reversibly inhibit conduction in single nerve fiber preparation of frog in a concentration of 3 × 10-10M. In the isolated electroplax of Electrophorus electricus higher concentrations block both transmission and conduction. Neither toxin is a potent acetylcholinesterase inhibitor. The mechanism of action of these toxins in blocking transmission and conduction has not yet been established.Keywords
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