Antibacterial Effect of Zinc Oxide in Vitro
- 1 January 1990
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery
- Vol. 24 (3) , 193-197
- https://doi.org/10.3109/02844319009041278
Abstract
Antibacterial activity, zinc concentrations and pH were measured in Müller-Hinton broth containing different amounts of zinc oxide and inoculated with Staphylococcus aureus (106 colony forming units/ml). The minimum inhibitory concentrations (MIC) of zinc oxide to different clinical isolates were determined using the Müller-Hinton agar dilution tests. Gram-positive bacteria were most susceptible. Gram-negative aerobic bacteria and streptococci were usually not inhibited even at the highest concentrations used (1024 μg/ml), but staphylococci—particularly some isolates of Staphylococcus epidermidis—were sensitive enough to allow determination of their MIC.Keywords
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