Relation between blood flow and morphology in islet organ of rat pancreas

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Abstract
By intra-arterial postmortem staining of the pancreas with hematoxylin after the administration of nonradioactive microspheres to anesthetized unfasted rats, mean single islet volume, pancreatic intensity of perfusion, percentage of pancreatic flow to islets, single islet blood flow and islet perfusion were measured. Perfusion of islet tissue was above average for very small islets and decreased with increasing islet size to become below average for very large ones. Details of the distribution of the total islet flow to subpopulations of islets grouped according to single islet size are shown pictorially.