Accelerated Immune Response Induced by D-L Penicillamine.

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Abstract
Summary Rabbits treated with D-L penicillamine for 28 days prior to intravenous injection of I131 labeled human serum albumin showed accelerated elimination of the antigen and correspondingly earlier appearance of free antibody, as compared with control animals. Graphic analysis of the radioactive clearance data indicates that the length of the induction period preceding antibody synthesis was shortened. Once immunity commenced, the slopes of the disappearance curves of both experimental and control group were parallel, suggesting no change in the rate of antibody production.