Forearm arterial pressure-volume relationships in man

Abstract
Pressure-volume (p-V) relationships of a segment of the forearm circulation have been measured in nine male healthy subjects. Forearm volume was measured using electrical impedance plethysmography, arterial transmural pressure by subtracting mean arterial pressure measured contralaterally in a finger from the pressure in a cuff placed over the sensing electrodes of the plethysmograph. A special two-phase measurement waveform was designed with which cuff pressure was first increased step wise to a suprasystolic level and held at that level for 120 s, then ramped down to zero pressure in another 300 s. The step phase inflation allowed the parameters of the interstitial liquids and total blood compartments to be estimated.