Methyl-Prostaglandin E2Analogues for Healing of Gastro-Duodenal Ulcers
- 23 February 1978
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Gastroenterology
- Vol. 13 (2) , 155-159
- https://doi.org/10.3109/00365527809181742
Abstract
117 patients were submitted to the randomized double-blind clinical trial. Methylated analogues of prostaglandin administered orally markedly suppressed gastric acid secretion and—in comparison to placebo—accelerated cicatrization of duodenal ulcers, but not of gastric ulcers. The resistance of some ulcers to healing was not dependent on gastric acid secretion.Keywords
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