Acute Purulent Meningitis Due toClostridium perfringens

Abstract
INTRACRANIAL infections caused by members of the genus clostridium are uncommon, especially among civilians. The problem of meningitis caused by anaerobic organisms was studied extensively by British and Russian workers in battle injuries during World War II.1 2 3 Purulent meningitis arising from clostridial infections was seen only as a complication of intracranial abscesses. Cairns et al.3 reported only 4 cases in which clostridium species were isolated from the cerebrospinal fluid. In these cases only a moderate cellular response was noted. They saw no small wound infections caused by the organism in which the intracranial cellular reaction could be regarded as severe. . . .

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