Constitutive mutation of cysJIH operon in a cysB deletion strain of Salmonella typhimurium
- 1 September 1979
- journal article
- research article
- Published by Springer Nature in Molecular Genetics and Genomics
- Vol. 175 (2) , 145-149
- https://doi.org/10.1007/bf00425530
Abstract
In a cysB deletion strain a new mutation, denoted cys-2332 was isolated, which causes the constitutive expression of the cysJIH operon. cys-2332 is closely linked to cysJIH and presumably is located in the initiator region of this operon, rendering its expression independent of the cysB gene product and the internal inducer O-acetyl-L-serine. The presence of salfite reductase (encoded by cysI and cysJ) activity in a cysB - cys-2332 double mutant indicates that cysG, which is not linked to cysJIH but is required for the synthesis of the sulfite reductase co-factor siroheme, is not controlled by cysB.This publication has 30 references indexed in Scilit:
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