Studies on in Vitro Anaphylaxis and Release of an Active Non-Histamine Material from Sensitized Guinea Pig Lung

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Abstract
Summary: The foregoing experiments show: That rat uteri, which are unaffected by ordinary doses of histamine, respond to some substance released by sensitized guinea-pig lung-tissue during anaphylactic shock.That sensitized circular and longitudinal uterine muscle from pregnant guinea pigs readily shows anaphylaxis and that the latter are just as sensitive and show a more severe type of reaction than virgin uterine muscle.That tissues, particularly intestinal, taken from 7 to 8 week foetuses of sensitized mothers, show a hypersensitive condition.

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