Biosynthesis of deoxyherqueinone in Penicillium herquei from [13C]acetate and [13C]malonate. Assembly pattern of acetate into the phenalenone ring system
- 1 January 1976
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 7,p. 258-260
- https://doi.org/10.1039/c39760000258
Abstract
The 13C n.m.r. spectra of deoxyherqueinone (I) enriched with sodium [1-13C]-, [2-13C]-, and [1,2-13C2]- acetate, and diethyl [2-13C]malonate by the fungus Penicillium herzuei indicate formation of the phenalenone ring system from seven intact acetate units and the mode of folding of the precursor heptaketide chain; a clear acetate ‘starter’ effect is apparent in the [2-13C]malonate enriched 13C-n.m.r. spectrum.This publication has 1 reference indexed in Scilit:
- Studies in the biosynthesis of fungal metabolites. 3. The biosynthesis of fungal perinaphthenonesBiochemical Journal, 1961