Complement-fixing Antibody Responses to ECHO Virus Types 12 and 19 of Patients with Enterovirus Infections.
- 1 February 1962
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 109 (2) , 364-369
- https://doi.org/10.3181/00379727-109-27204
Abstract
Sera from 167 patients with various enterovirus infections were tested against uninactivated CF antigens to ECHO virus types 12 and 19. Four-fold or greater rises in CF antibody titer, unassociated with the presence of neutralizing antibody to these 2 ECHO virus types, were seen in an appreciable proportion of patients infected with ECHO 4, 6, 9 and 11 viruses, possibly indicating antigenic relationships of the viral moieties responsible for production of CF antibodies in man. No evidence was seen of a relationship between ECHO types 12 and 19 and ECHO 5, ECHO 10 (reoviruses) or ECHO 14, nor was there any good evidence of a relationship between these 2 ECHO virus types and the Coxsackie group A, Coxsackie group B or polio-virus types studied.Keywords
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