Immunological relationships of Candida albicans and its transformants to Actinomycetales

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Abstract
Immunochemical properties of a parental strain of C. albicans and of four transformants, obtained by exposing competent C. albicans cells to deoxyribonucleic acid (DNA) of Mycobacterium tuberculosis, were examined by selected methods. It was found that the cytoplasms of all the Candidas shared at least one antigen, but the transformants alone contained two additional antigenic factors. The cytoplasm preparations of all the Candidas were found immunologically related to M. microti, M. kansasii, M. abscessus, and to some strains of Runyon's Group IV, as well as to many Nocardias, Streptomycetes, Actinomycetes, Mycococci, and Dermatophili. The transformants were also related to the non-chromogenic mycobacteria.

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