A Synthesis of 1,5-DI-O-Acetyl-3-Azido-2,3-Dideoxy-D-Ribofuranose
- 1 March 1988
- journal article
- comunication
- Published by Taylor & Francis in Journal of Carbohydrate Chemistry
- Vol. 7 (1) , 271-275
- https://doi.org/10.1080/07328308808058920
Abstract
The renewed interest in azido-nucleosides, particularly when the aziodo group is present at position 3, has been intensified1 since the approval of 3′-azido-thymidine (1) for the treatment of AIDS. Moreover, 3′-amino-2,3-dideoxy-nucleosides are also important due to various biological activities associated 3-5 with them. In dealing with the synthesis of such molecules, 3-azido-2,3-dideoxy-pentoses have been realised as valuable synthons.Keywords
This publication has 2 references indexed in Scilit:
- 3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro.Proceedings of the National Academy of Sciences, 1985
- Aminonuclosides and Their Derivatives; XII1. A New Synthesis of 1-O-Methyl-3-azido-2,3-dideoxy-D-ribofuranoseSynthesis, 1984