ASCITES FORM OF HUMAN MAMMARY-CARCINOMA TRANSPLANTABLE IN NUDE-MICE
- 1 January 1979
- journal article
- research article
- Vol. 30 (5) , 245-249
Abstract
Mammary carcinoma cells from pleural effusion of a patient were inoculated into the peritoneal cavity of nude mice and a large amount of ascites was produced about 120 days later. From the ascites, serial passages in the same form were successful in nude mice by i.p. injection of 107 or more cells. The ascites cells retained a morphology almost similar to that of the patient tumor cells, whereas specific estrogen-binding proteins in the cytoplasm disappeared after growing in male nude mice. The results were compared with other established human cancer cell lines in nude mice.This publication has 7 references indexed in Scilit:
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