Acute West Nile virus neuroinvasive infections: Cross‐reactivity with dengue virus and tick‐borne encephalitis virus
- 11 August 2011
- journal article
- research article
- Published by Wiley in Journal of Medical Virology
- Vol. 83 (10) , 1861-1865
- https://doi.org/10.1002/jmv.22180
Abstract
Cross-reactions in serology are common among flaviviruses. During the outbreak of West Nile virus (WNV) infections in Greece in 2010, WNV IgM-positive serum and cerebrospinal fluid samples were tested for the presence of IgM and IgG antibodies against Dengue virus (DENV) and tick-borne encephalitis virus. Higher cross-reactivity was observed in IgM antibodies between WNV and DENV; however, the index of the WNV antibodies was in all cases higher than that of the DENV antibodies. There is a need for caution when evaluating serologic results of flaviviral infections, while efforts have to be focused on the development of diagnostic assays with increased specificity. J. Med. Virol. 83:1861–1865, 2011.Keywords
This publication has 20 references indexed in Scilit:
- Genetic Characterization of West Nile Virus Lineage 2, Greece, 2010Emerging Infectious Diseases, 2011
- Usutu virus in ITALY: An emergence or a silent infection?Veterinary Microbiology, 2011
- Genetic Study of the Distribution of Greek Goat Encephalitis Virus in GreeceVector-Borne and Zoonotic Diseases, 2008
- Greek Goat Encephalitis Virus Strain Isolated fromIxodes ricinus,GreeceEmerging Infectious Diseases, 2008
- Epidemiological Study of Tick-Borne Encephalitis Virus in Northern GreeceVector-Borne and Zoonotic Diseases, 2007
- A single positively selected West Nile viral mutation confers increased virogenesis in American crowsNature Genetics, 2007
- Evaluation of a Diagnostic Algorithm Using Immunoglobulin M Enzyme-Linked Immunosorbent Assay To Differentiate Human West Nile Virus and St. Louis Encephalitis Virus Infections during the 2002 West Nile Virus Epidemic in the United StatesClinical and Vaccine Immunology, 2004
- Performance of Immunoglobulin G (IgG) and IgM Enzyme-Linked Immunosorbent Assays Using a West Nile Virus Recombinant Antigen (preM/E) for Detection of West Nile Virus- and Other Flavivirus-Specific AntibodiesJournal of Clinical Microbiology, 2004
- Detection of IgG and IgM to West Nile VirusAmerican Journal of Clinical Pathology, 2003
- West Nile Virus: A Reemerging Global PathogenEmerging Infectious Diseases, 2001