IMMUNOHISTOCHEMICAL DIAGNOSIS OF TOXOPLASMOSIS IN FETUSES AND FETAL MEMBRANES OF SHEEP

  • 1 March 1987
    • journal article
    • research article
    • Vol. 48  (3) , 348-351
Abstract
A peroxidase antiperoxidase technique was developed for visualizing intact Toxoplasma gondii and its antigenic residues in sections of formalin-fixed, paraffin-embedded tissue from fetal membranes recovered from ewes with induced toxoplasmosis. The peroxidase antiperoxidase method was specific and sensitive, allowing the detection of T. gondii antigen even in severely decomposed tissues. Toxoplasma gondii infection was most commonly demonstrated in the cotyledons, heart, lungs, brain, and skeletal muscles of the fetus.