The Effects of Accelerated Carbon Nuclei and Other Radiations on the Survival of Haploid Yeast: I. Dosimetry of the Cyclotron Beams

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Abstract
In the investigation reported here, cell survival of the haploid yeast, Saccharomyces cerevisiae, was studied for LET values ranging between 2 and 500 kev/[mu]. In order to carry out this study, special experimental apparatus was developed for the irradiation of yeast cells with cyclotron beams of 20-Mev deuterons, 40-Mev alpha particles, and 120-Mev carbon nuclei. The 1st paper of this pair describes the physical measurements necessary for the accurate determination of the average linear energy transfer and the doses delivered by the various cyclotron beams. The dose calculation from ionization-chamber measurements is given, along with the estimated uncertainties that produce an over-all error ranging between 5 and 10%.

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