The Biosynthesis of A2E, a Fluorophore of Aging Retina, Involves the Formation of the Precursor, A2-PE, in the Photoreceptor Outer Segment Membrane
Open Access
- 1 September 2000
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 275 (38) , 29354-29360
- https://doi.org/10.1074/jbc.m910191199
Abstract
No abstract availableKeywords
This publication has 22 references indexed in Scilit:
- Insights into the Function of Rim Protein in Photoreceptors and Etiology of Stargardt's Disease from the Phenotype in abcr Knockout MiceCell, 1999
- Mutation of the Stargardt Disease Gene ( ABCR ) in Age-Related Macular DegenerationScience, 1997
- Total Synthesis of the Ocular Age Pigment A2-E: A Convergent PathwayJournal of the American Chemical Society, 1997
- A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Starqardt macular dystrophyNature Genetics, 1997
- Formation of lipofuscin-like fluorophores by reaction of retinal with photoreceptor outer segments and liposomesMechanisms of Ageing and Development, 1996
- Ocular Age Pigment “A2-E”: An Unprecedented Pyridinium BisretinoidJournal of the American Chemical Society, 1996
- LIPOFUSCIN FLUOROPHORE INHIBITS LYSOSOMAL PROTEIN DEGRADATION AND MAY CAUSE EARLY STAGES OF MACULAR DEGENERATIONGerontology, 1995
- Rod Outer Segment Retinol Dehydrogenase: Substrate Specificity and Role in PhototransductionBiochemistry, 1994
- Lipofuscin autofluorescence: Evidence for vitamin A involvement in the retinaMechanisms of Ageing and Development, 1987
- Lipid to Protein Chromophore Transfer in the Photolysis of Visual PigmentsNature, 1969