EFFECT OF CRUDE AND PURIFIED HCG ON LYMPHOCYTE BLASTOGENESIS

  • 1 January 1976
    • journal article
    • research article
    • Vol. 47  (5) , 557-561
Abstract
Crude APL [anterior pituitary-like hormone] hCG [human chorionic gonadotropin] completely inhibited blastogenesis induced by phytohemagglutinin, pokeweed mitogen or concanavalin A in normal [human] lymphocytes and lymphocytes obtained from cancer patients. Phenol in quantities comparable to its concentration in commercial lyophilized APL hCG also completely inhibited all 3 mitogenic responses. Similar doses of highly purified hCG had no inhibitory effect; higher concentrations produced only slight inhibition. .beta.-hCG had a partial (< 50%) inhibitory effect that was dose-independent and non-reproducible.

This publication has 1 reference indexed in Scilit: