GROUP-I PEPSINOGENS IN SERUM .1. NORMAL RANGE, AGE AND SEX RELATION, DIURNAL RHYTHM, SEASONAL-VARIATION, AND DISTRIBUTION IN ABO BLOOD-GROUPS

  • 1 January 1984
    • journal article
    • research article
    • Vol. 19  (8) , 1114-1118
Abstract
The concentration of group I pepsinogens (PG I) in serum was determined in 235 healthy persons and hospital controls. The concentration was significantly higher in males. Correction of PG I with regard to body weight or lean body mass eliminated the sex difference but not the weak correlation with age. The normal range was 0.60-3.3 ng PG I/ml serum per kg body weight. For comparison with other PG I studies another normal range, 46-211 ng PG I/ml serum, was calculated as the 95% interpercentile range of the present PG I concentrations. In a study of diurnal rhythm and in a 6 mo. study of seasonal variation, no significant variation of PG I in serum was found. Serious non-gastric surgical disease did not influence the PG I level in serum. The PG I levels in blood groups O, A and B did not differ significantly.