Spectrum of neuropsychiatric complications in 791 cases of typhoid fever
Open Access
- 1 April 1997
- journal article
- Published by Wiley in Tropical Medicine & International Health
- Vol. 2 (4) , 314-318
- https://doi.org/10.1111/j.1365-3156.1997.tb00145.x
Abstract
Summary Over a 6‐year period, we studied 791 patients with multidrug‐resistant typhoid fever, of whom 665 individuals (84%) developed neuropsychiatric manifestations. These were: acute confusional state (73%); myelitis (6%); cerebellitis (1%); parkinsonism (1%); acute psychosis (0.6%); meningo‐encephalitis (0.5%); encephalitis (0.25%); sensory motor polyneuropathy, polymyositis, acute schizophrenia and bizarre neurological syndromes (0.12% each). Severe parkinsonian rigidity and meningo‐encephalitis are associated with significant morbidity but very low mortality (0.5%).Keywords
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