HEMOPHILUS INFLUENZAE MENINGITIS: REPORT OF TWO CASES IN ADULTS

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Abstract
Acute purulent meningitis, occurring in a 42-year-old male and a 62 -year-old female, was shown to have been caused by Hemophilus influenzae, type b. Recovery resulted following the early administration of penicillin and sulfadiazine, and the later administration of streptomycin in the 1st case and chloram-phenicol in the 2nd. Both strains of H. influenzae were sensitive to penicillin in vitro. However, penicillin and sulfadiazine are not advocated for the primary treatment of H. influenzae meningitis, since other chemotherapeutic agents, principally chloramphenicol and streptomycin, with or without sulfonamide, have been established on clinical grounds as being more effective.