Measurement System for Noninvasive Dynamic Optical Topography
- 1 January 1999
- journal article
- Published by SPIE-Intl Soc Optical Eng in Journal of Biomedical Optics
- Vol. 4 (4) , 414-7
- https://doi.org/10.1117/1.429940
Abstract
We have developed a 24-channel simultaneous measurement system for optical topography that noninvasively obtains dynamic images of brain activity using near-infrared light. To evaluate the system performance, we utilized a dynamic phantom containing a rotating absorber in a cylindrical scattering medium. In this system, eight incident and eight detecting optical fibers are arranged alternately at square lattice points on the phantom. The phantom is illuminated with light of two wavelengths (780 and 830 nm) from each incident fiber. Reflected light is received by the detecting fibers, each of which is connected to an avalanche photodiode. Multiple light intensity modulation and lock-in detection are used to enable highly sensitive measurement with negligible cross talk for multichannel measurement. In the phantom measurement, we obtained topographic dynamic images of the absorber rotating in the medium with a temporal resolution of 0.5 s over a measurement area of 90 mm×90 mm. © 1999 Society of Photo-Optical Instrumentation Engineers.Keywords
This publication has 12 references indexed in Scilit:
- Noninvasive near‐infrared topography of human brain activity using intensity modulation spectroscopyOptical Engineering, 1996
- Near-infrared topographic measurement system: Imaging of absorbers localized in a scattering mediumReview of Scientific Instruments, 1996
- Spatial and temporal analysis of human motor activity using noninvasive NIR topographyMedical Physics, 1995
- Dynamic multichannel near-infrared optical imaging of human brain activityJournal of Applied Physiology, 1993
- Near infrared spectroscopy (NIRS): A new tool to study hemodynamic changes during activation of brain function in human adultsNeuroscience Letters, 1993
- Human Visual Cortical Function during Photic Stimulation Monitoring by Means of near-Infrared SpectroscopyJournal of Cerebral Blood Flow & Metabolism, 1993
- Cognition-activated low-frequency modulation of light absorption in human brain.Proceedings of the National Academy of Sciences, 1993
- Intracerebral penetration of infrared lightJournal of Neurosurgery, 1992
- A review of the optical properties of biological tissuesIEEE Journal of Quantum Electronics, 1990
- Time resolved reflectance and transmittance for the noninvasive measurement of tissue optical propertiesApplied Optics, 1989