Purine nucleoside phosphorylase polymorphism in sheep erythrocytes
- 1 June 1977
- journal article
- research article
- Published by Springer Nature in Biochemical Genetics
- Vol. 15 (5-6) , 439-444
- https://doi.org/10.1007/bf00520189
Abstract
A polymorphism of purine nucleoside phosphorylase is described in sheep erythrocytes. Two isozymes were distinguished electrophoretically, one with high activity (NP-1) and one with low activity (NP-2). Breeding data suggest that the two isozymes are the product of two codominant alleles, NP 1and NP 2. The K m 's for inosine did not differ between NP-1 and NP-2; however, NP-2 had a lower pH optimum and was relatively unstable when incubated at 48 C.This publication has 9 references indexed in Scilit:
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