A pharmcokinetic model for enterohepatic circulation of an analgesic l-1,4-dimethyl-10-hydroxy-2,3,4,5,6,7-hex-ahydro-1,6-methano-1H-4-benzazonine hydrobromide (l-ST-2121) in rats.
- 1 January 1981
- journal article
- research article
- Published by Pharmaceutical Society of Japan in Journal of Pharmacobio-Dynamics
- Vol. 4 (7) , 461-468
- https://doi.org/10.1248/bpb1978.4.461
Abstract
Simple compartment models are presented to describe various aspects of enterohepatic circulation pharmacokinetics of an analgesic (l-ST 2121) in rats. Appearance of trigonometric functions in the analytically integrated blood level equation adequately describes the periodic nature of the process.This publication has 1 reference indexed in Scilit: