A pharmcokinetic model for enterohepatic circulation of an analgesic l-1,4-dimethyl-10-hydroxy-2,3,4,5,6,7-hex-ahydro-1,6-methano-1H-4-benzazonine hydrobromide (l-ST-2121) in rats.

Abstract
Simple compartment models are presented to describe various aspects of enterohepatic circulation pharmacokinetics of an analgesic (l-ST 2121) in rats. Appearance of trigonometric functions in the analytically integrated blood level equation adequately describes the periodic nature of the process.