Creatine, Creatinine and Total Body Potassium in Relation to Muscle Mass in Children

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Abstract
Duplicate 24-hour preformed creatinine and creatine excretion levels were estimated in 40 convalescent infants and children. The creatinine output for each individual was reasonably constant, but somewhat lower than figures reported by other investigators for children over 3 years of age. The total creatinine and creatine outputs showed much greater variation, i.e. the creatine was more variable. In 13 children in addition, an attempt to estimate muscle mass was made by the following methods: measurement of weight, height, limb girth and fat thickness; measurement of muscle shadow in soft tissue radiographs; estimation of total exchangeable potassium using K42. No correlation could be found between creatinine index, estimation of muscle mass from body measurements, estimation of muscle mass from soft tissue radiograph measurements and total exchangeable potassium.

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