The Rabbit Ear Chamber: A UniqueIn VivoModel for the Continuous Observation of Implanted Biomaterials

Abstract
The rabbit ear chamber provides a unique system for viewing an in vivo environment from outside the body. The plastic chamber, modified for our use, is described. Once surgically implanted into the ear of a Laboratory Lop rabbit, a thin tissue bed which grows between the layers of the chamber can be viewed through the microscope. The absorption of biomaterials placed into the chamber can then be observed as a dynamic process.