Some derivatives of 2- and 3-phenylthiophen

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Abstract
Some 2-(4-substituted phenyl)thiophens and their 3-methyl derivatives have been used to prepare substituted methylamines, ethylamines, and acetic acids with potential biological activity. Similar derivatives from 3-phenylthiophen and its 2-methyl derivative have also been prepared. Electrophilic substitution of 3-methyl-2-phenylthiophen and of 2-methyl-3-phenylthiophen takes place in the vacant α-position of the thiophen ring.