Abstract
Fusion of sensitive and killer plasmodia of Physarum polycephalum caused a change in membrane composition which did not occur after fusion of two sensitive plasmodia. This change, which was mainly the result of an increase in the synthesis of phosphatidylethanolamine, began 1.5 h after fusion. Heat production and oxygen consumption declined during the processes which underlie the lethal reaction which destroys the fused plasmodia of sensitive and killer strains.