Aging Changes in the Kinetics of Lamellar Bone Resorption in Normal Human Rib

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Abstract
Curves of the rate of evolution of the bone resorption process that accompanies osteon production are obtained by measurements on histological sections of ribs from 105 meta-bolically normal people aged 10 to 70 years. Time domain transformations of histograms of the circumferences of complete and incomplete resorption spaces are determined. At all ages, the initial phase of a resorption process is less rapid than the last phase. There is a partly reversing age-dependent change. The curve of the 35 year old is appreciably different from that of the adolescent and the 65 year old. There is a moderate net change in kinetics between the age extremes studied.