The Association of Age with Aspirin Esterase Activity in Human Liver

Abstract
The activity of the phase 1 enzyme aspirin esterase was studied in liver tissue from 16 patients, aged 45–88 years. No correlation between age and enzyme activity was found in post-mitochondrial, cytosolic and microsomal fractions. These results provide further evidence that age is not a major determinant of the activity of hepatic drug-metabolizing enzymes in man.

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