Genetic and cytogenetic studies of the malate dehydrogenases of Drosophila melanogaster
- 1 October 1979
- journal article
- research article
- Published by Springer Nature in Biochemical Genetics
- Vol. 17 (9-10) , 947-956
- https://doi.org/10.1007/bf00504314
Abstract
Genetic and cytogenetic locations of the structural genes for the NAD-dependent malate dehydrogenases have been studied. The mitochondrial form (mMDH) is coded for by a gene (Mdh) found at 62.6 on the third chromosome and included in Df(3R)P14, which includes 90C2–91A3 in the salivary gland chromosomes. Based on its inclusion within several J (Jammed; 2–41.0) deficiencies, the structural gene (cMdh) for the cytoplasmic form (cMDH) was determined to lie in region 31B-E, confirming the earlier finding of Grell. Flies lacking any cMDH activity (cMdhn-γ10069/ Df(2L)J-der-27) were both viable and fertile.This publication has 23 references indexed in Scilit:
- Genetic control of mitochondrial malate dehydrogenases: evidence for duplicated chromosome segments.Proceedings of the National Academy of Sciences, 1977
- INTERACTING GENE-ENZYME SYSTEMS IN DROSOPHILAAnnual Review of Genetics, 1976
- Regulation of enzyme activities inDrosophila: I. The detection of regulatory loci by gene dosage responsesGenetics Research, 1974
- Regulation of enzyme activities inDrosophila: II. Characterization of enzyme responses in aneuploid fliesGenetics Research, 1974
- Comparative analysis of malate dehydrogenases of Drosophila melanogasterBiochemical Genetics, 1973
- Isozyme variability in species of the genus Drosophila. VII. Genotype-environment relationships in populations of D. melanogaster from the eastern United StatesBiochemical Genetics, 1973
- Mitochondrial malate dehydrogenase and malic enzyme: Mendelian inherited electrophoretic variants in the mouseBiochemical Genetics, 1970
- The degree of polymorphisms in enzymes involved in energy production compared to that in nonspecific enzymes in two Drosophila ananassae populations.Proceedings of the National Academy of Sciences, 1968
- Mitochondrial Malate Dehydrogenase: A New Genetic Polymorphism in ManScience, 1967
- Genetic Variant of Human Erythrocyte Malate DehydrogenaseNature, 1967