THE EFFECT OF LOCALLY APPLIED IPRATROPIUM AEROSOL ON THE NASAL METHACHOLINE CHALLENGE IN PATIENTS WITH ALLERGIC AND NONALLERGIC RHINITIS

  • 1 February 1986
    • journal article
    • research article
    • Vol. 56  (2) , 162-166
Abstract
The effect of local pretreatment with ipratropium versus placebo aerosol on nasal methacholine challenge was studied in a double-blind, crossover trial. Fourteen allergic and ten non-allergic patients suffering from rhinitis participated in this study. It can be concluded that intranasal administration of ipratropium has a suppressive effect on hypersecretion and sneezing, but has no influence on nasal airway resistance.

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