Regulation of Development, Survival and Neoplastic Growth of Mast Cells through the c-kit Receptor
- 1 January 1995
- journal article
- review article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 107 (1-3) , 54-56
- https://doi.org/10.1159/000236929
Abstract
Signaling through the c-kit receptor tyrosine kinase (Kit) is essential for development and survival of mast cells but not of basophils. Moreover, we recently found an activation mutation of Kit in several tumor mast cell lines.Keywords
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