ENZYMIC RESPONSES FOLLOWING ADMINISTRATION OF ACTH TO BIRDS

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Abstract
The physiological function of the bursa of Fabricius (bursa), a gland peculiar to young Aves only, is not well established (see Glick, 1960; Perek & Eilat, 1960; Perek & Bedrak, 1962). This communication presents the findings of a quantitative study in which the responses of three oxidative enzymes of liver and kidney, namely xanthine oxidase, succinoxidase and cytochrome oxidase, were compared in Leghorn cockerels with and without removal of the bursa, following administration of ACTH. Bursectomy was performed at the age of 2 weeks. At the age of 7 weeks thirty-two birds of comparable body weight, half of which were bursectomized, were selected as the experimental groups. To eight birds of each group (Table 1) 1 ml. saline solution per bird was administered, and to the remaining eight, 1 ml. of ACTH† in saline, 10 i.u. per bird. All injections were given intravenously. The birds were killed by cervical dislocation

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